Blinatumomab for Minimal Residual Disease Clearance in B-Acute Lymphoblastic Leukemia
Objective: To evaluate the efficacy, safety, and clinical impact of blinatumomab across the treatment continuum of B-cell acute lymphoblastic leukemia. Design…
Objective: To evaluate the efficacy, safety, and clinical impact of blinatumomab across the treatment continuum of B-cell acute lymphoblastic leukemia. Design…
Introduction: The management of HF has evolved significantly with the introduction of novel therapeutic agents and biomarker-guided strategies. NT-proBNP (N-ter…
Objectives: This study aims to evaluate the prognostic value of pretreatment hematological and biochemical markers, including serum albumin, globulin, and alkal…
Background: Urosepsis occurs in uncontrolled diabetes mellitus (DM) with a high morbidity because of changing beta-lactam resistance, which may become a problem…
Objectives: To study the epidemiological profile, clinical presentation, severity assessment using the Peradeniya Organophosphorus Poisoning (POP) score, treatm…
Objective: To describe an exceptionally rare occurrence of chronic myeloid leukemia developing in the setting of relapsed refractory classical Hodgkin lymphoma…
Objective: To evaluate efficacy, durability, and safety of next-generation chimeric antigen receptor T-cell therapies in relapsed or refractory acute lymphoblas…
Context: Reproductive tract infections (RTIs) are common health problems among women of reproductive age and contribute significantly to morbidity, particularl…
Background: Capecitabine–oxaliplatin (CAPOX) is a commonly used chemotherapy regimen in gastric and colorectal malignancies. Although its efficacy has been well…
Objective: To study correlation between umbilical cord blood albumin (CBA) and neonatal hyperbilirubinemia. Methods: From January 2023 to December 2023, a prosp…
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common, dose-limiting toxicity of neurotoxic chemotherapy that significantly impairs quality…
Background: Root canal treatment failure that causes re-infection can occur due to various causes, one of which is by Candida albicans fungus in the root canal…
Background: Bioinformatics is a scientific sub-discipline that covers the area of biology at multi-disciplinary levels of microbiology, immunology, molecular bi…
Background: Inappropriately prescribed antibiotics in pediatric outpatient care remain one of the most significant global drivers of antimicrobial resistance. D…
Background: Ectopic pregnancy (EP) is a primary cause of maternal health issues and fatalities during the first trimester. With advancements in treatments such…
Background: Anemia is a frequent comorbidity in women with gynecological malignancies, adversely affecting tolerance to surgery, chemotherapy, and radiotherapy…
Objective: The aim of this study is to identify the rate of major and minor disagreements with diagnoses from external institutions for patients with head and n…
Objective: To review recent advancements in the understanding, diagnosis, and management of keratoconus, emphasizing the role of Scheimpflug imaging and the Bel…
Objectives: The study evaluates revision dacryocystorhinostomy (DCR) outcomes with intra-operative mitomycin-C, addressing the need for intubation in unsuccessf…
Background: Pregnancy-associated hypertensive disorders (HDP) are important predictors of maternal and neonatal health outcomes, particularly for rurality-based…
Background: Inguinal hernia (IH) refers to the abdominal void protrusion via the inguinal canal. Tension-free hernioplasty (OTFH) is the standard procedure for…
The agenesis of maxillary lateral incisors is a common dental anomaly that often presents aesthetic and functional challenges for patients and orthodontists. Pa…
Background: Infantile Hypertrophic Pyloric Stenosis (IHPS) is the leading etiology of gastric outlet obstruction in infancy, with progressive pyloric musculatur…
Introduction: Melasma is an irregular brown or greyish-brown symmetric facial hyper melanosis, causing significant cosmetic concern and psychological morbidity…
Background: Pin site infection remains the most common complication following external fixation, with reported incidence rates varying widely. Understanding the…
Objective: Interest in off pump technique has markedly expanded in recent years. It has been shown that peroperative complications and mortality rates are reduc…
Background: Ectopic pregnancy is a life-threatening condition and a substantial contributor to maternal morbidity. Advancement in ultrasonographic and biochemic…
Objective: To evaluate whether hysteroscopic-guided intrauterine platelet-rich plasma (PRP) with estradiol improves endometrial thickness and vascularity, and i…
The use of injectable fillers in the facial region has grown significantly in recent decades, primarily for aesthetic rejuvenation and for the treatment of faci…
Clostridioides difficile infection remains a leading cause of healthcare-associated diarrhea, linked primarily to broad-spectrum antibiotic use and gut microbio…
Introduction: Ovarian metastases from gastrointestinal cancers (Krukenberg tumors) are rare, accounting for 1–2% of all ovarian malignancies. Despite their low…
Background: Cardiovascular complications are rare in tuberculosis. It causes severe morbidity and mortality. There is paucity of data on cor pulmonale as a comp…
Diabetic foot ulcers (DFUs) are a major global health concern, often leading to infection, hospitalization, and in severe cases, limb amputation. This case seri…
Introduction: Nimesulide-Paracetamol fixed-dose combination is widely used for managing acute painful conditions, yet real-world evidence remains limited. This…
Background: Lung cancer is the third-leading cause of death in cancer patients among both men and women in Indonesia. About 80% of lung cancer types are non-sma…
Bronchopleural fistula (BPF) is a severe complication of pulmonary tuberculosis, particularly prevalent in high TB incidence regions like Indonesia. We managed…
This case report outlines the effective management and outcome of a 26 years old male patient with lumbar scoliosis and multiple large left ureteric calculi wit…
Background: Postpartum psychiatric illnesses, from the ubiquitous but generally self-limited baby blues to the comparatively unusual but potentially fatal postp…
Surgical techniques for managing chronic migraines are gaining traction, especially for patients who do not respond to conventional pharmacological treatments…
Migraine is a prevalent and disabling neurological condition characterized by recurrent, intense headaches, often accompanied by nausea, light sensitivity, and…
Objectives: Oral isotretinoin is an effective treatment for moderate to severe acne but is often associated with systemic side effects and psychological impact…
Background: Lens-induced glaucoma (LIG) is still a major cause of irreversible blindness in developing countries, largely because of delayed treatment and diagn…
Background: Intertrochanteric fractures, unstable particularly (AO/OTA 31-A3), is difficult to treat. Proximal femoral nailing (PFN) has emerged as a convenient…
Diarrhea remains a major cause of child mortality in sub-Saharan Africa. Although Oral Rehydration Solution is a highly effective intervention, its utilization…
Background: Retinoblastoma (RB) is the most common intraocular malignancy of childhood, with an excellent primary cure rate. However, survivors-particularly tho…
Vulvar cancer constitutes 5% of the malignancies of the female genital tract and 95% of the vulvar cancers are squamous cell carcinoma, followed by melanoma, sa…
Background: Buccal mucosal graft urethroplasty (BMGU) is now the gold standard in the treatment of anterior urethral strictures, particularly of long lengths or…
Objective: To assess the clinical effectiveness and safety of Co-Amoxiclav in the real-world treatment of dental infections. Design: Multicenter, retrospective…
Introduction: Thyroid is a butterfly shaped endocrine gland situated in front of the neck. It secretes the hormones T3 and T4, playing a prime role in the metab…
Background: Emerging evidence suggests that the gut microbiome plays a critical role in the pathophysiology of psychiatric disorders, particularly depression an…