Evaluation of Factors Affecting the Outcome of Acute Ischaemic Stroke in Elderly Patients: A Tertiary Care Center Study

Authors

Mohammed Fasahatulla Khan  1 , Hiya Mehta  2 , Abhiram Bhave  3 , Sangeeta Pednekar  4 , Shreekumar S  5 , Akshay Malunjkar  6 , Rahul Milind Patil  7 , Siddhesh Shailesh Mohite  8 , Abhijit Anant Ghase  9 , Charulata Londhe  10 , Raed A. Kalsekar  11 , Alhad A. Mulkalwar  12
Senior Resident, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 1 , Junior Resident, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 2 , Junior Resident, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 3 , Professor, Head of Unit, Geriatrics Services In-Charge, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 4 , Junior Resident, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 5 , Junior Resident, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 6 , Junior Resident, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 7 , Junior Resident, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 8 , Junior Resident, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 9 , Associate Professor, Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Maharashtra, India. 10 , 3rd Year Undergraduate Student, Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Maharashtra, India. 11 , Tutor, Department of Pharmacology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune,  Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune (Deemed to be University), Pune, Maharashtra India. 12
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Abstract

Introduction: Stroke is a major cause of mortality and disability, with elderly patients at higher risk. Ischemic stroke, the most common type, results from embolic or thrombotic arterial occlusion. Prognostic assessment is essential for guiding management and rehabilitation. This study evaluates prognostic factors in elderly acute ischemic stroke patients, particularly the National Institutes of Health Stroke Scale (NIHSS) and Orpington Prognostic Scale (OPS). Materials and Methods: This prospective observational study included 50 patients aged ≥60 years diagnosed with acute ischemic stroke. Clinical history, neurological exams, NIHSS scoring, and radiological investigations were conducted. Follow-up at six months assessed functional recovery using OPS. Statistical analysis was performed using SPSS v20.0. Results: The mean age was 71 years, with a male predominance (66%). Hypertension (66%) and diabetes (48%) were key risk factors. Fever (>38°C) correlated with poor outcomes (55% mortality/worsening). NIHSS >21 and GCS <8 predicted worse prognosis. At follow-up, 60% improved, while 14% worsened or died. Conclusion: Strict blood pressure and glucose control, early rehabilitation, and stroke unit care improve prognosis. NIHSS and OPS are valuable for assessing stroke severity and outcomes.

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Evaluation of Factors Affecting the Outcome of Acute Ischaemic Stroke in Elderly Patients: A Tertiary Care Center Study. (2025). Annals of Medicine and Medical Sciences, 234-239. https://doi.org/10.5281/
Original Article

Copyright (c) 2025 Mohammed Fasahatulla Khan, Hiya Mehta, Abhiram Bhave, Sangeeta Pednekar, Shreekumar S, Akshay Malunjkar, Rahul Milind Patil, Siddhesh Shailesh Mohite, Abhijit Anant Ghase, Charulata Londhe, Raed A. Kalsekar, Alhad A. Mulkalwar

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