Impact of COVID -19 Pandemic on Feto-maternal Outcome: A Single Center Based Study from Central India
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Abstract
Background: Global surge of COVID-19 had put concerns on the maternal and neonatal wellbeing. The present study was aimed to assess the impact of COVID-19 on feto-maternal outcome. Method: A single-center based retrospective analytical study with pregnancy outcome data of all singleton pregnancy from period 01 Apr 2019 to 31 Mar 2021 was conducted. Comparison was done between pre COVID-19 period and COVID-19 pandemic period. Maternal age, gravida, parity, mode of delivery etc were the parameters analysed. Chi-square/Kruskal Wallis and Mann Whitney U Test were performed with SPSS Ver 20.0 software and p value < 0.05 was considered statistically significant. Results: The statistics of 421 singleton deliveries during COVID-19 was compared with 554 deliveries a year prior COVID-19. It was observed that caesarean delivery (LSCS) accounted for 51.07%, Low Birth Weight (LBW) proportion was increased slightly, and pre-term deliveries were decreased. Also 22% increase in LSCS and a threefold increase in Intra Uterine Fetal Demise (IUFD) proportion were noted. The odd ratio of caesarean delivery was 2.5 times higher than pre-COVID-19 period. Post LSCS pregnancy accounted 43.12% of all LSCS performed and contributed as a key indication for LSCS. Conclusions: The research explores the outcome of pregnancies in India during and after the COVID-19 lockdown. The COVID-19 pandemic was found to have influenced various aspects of feto-maternal outcome. Not too many significant negative effects were established on pregnancy outcomes other than high incidence of caesarean delivery.
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Copyright (c) 2025 Tarini Singh, Debkalyan Maji, Parikshit Debnath

This work is licensed under a Creative Commons Attribution 4.0 International License.
Creative Commons License All articles published in Annals of Medicine and Medical Sciences are licensed under a Creative Commons Attribution 4.0 International License.
Tarini Singh, Jr Consultant, Department of Obstetrics & Gynaecology, Sarwal Govt Hospital, UT of J & K, India.
Jr Consultant, Department of Obstetrics & Gynaecology, Sarwal Govt Hospital, UT of J & K, India.
Debkalyan Maji, Associate Professor, Department of Obstetrics & Gynaecology, Command Hospital (EC), Kolkata, West Bengal, India.
Associate Professor, Department of Obstetrics & Gynaecology, Command Hospital (EC), Kolkata, West Bengal, India.
Parikshit Debnath, Associate Professor, Department of Swasthavritta & Yoga, IAA Medical College & University Hospital, Meghalaya, India.
Associate Professor, Department of Swasthavritta & Yoga, IAA Medical College & University Hospital, Meghalaya, India.
[1] Bogin B, Varea C. COVID-19, crisis, and emotional stress: A biocultural perspective of their impact on growth and development for the next generation. American Journal of Human Biology. 2020;32(5):e23474.
[2] Wong SF, Chow KM, Leung TN, Ng WF, Ng TK, Shek CC, et al. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. American Journal of Obstetrics & Gynecology. 2004;191(1):292-7.
[3] Li AM, Ng PC. Severe acute respiratory syndrome (SARS) in neonates and children. Arch Dis Child Fetal Neonatal Ed. 2005;90(6):F461-F5.
[4] Shek CC, Ng PC, Fung GP, Cheng FW, Chan PK, Peiris MJ, et al. Infants born to mothers with severe acute respiratory syndrome. Pediatrics. 2003;112(4):e254. Epub 2003/10/03.
[5] Dang D, Wang L, Zhang C, Li Z, Wu H. Potential effects of SARS-CoV-2 infection during pregnancy on fetuses and newborns are worthy of attention. Journal of Obstetrics and Gynaecology Research. 2020;46(10):1951-7.
[6] Been JV, Burgos Ochoa L, Bertens LCM, Schoenmakers S, Steegers EAP, Reiss IKM. Impact of COVID-19 mitigation measures on the incidence of preterm birth: a national quasi-experimental study. Lancet Public Health. 2020;5(11):e604-e11. Epub 2020/10/14.
[7] Sentilhes L, De Marcillac F, Jouffrieau C, Kuhn P, Thuet V, Hansmann Y, et al. Coronavirus disease 2019 in pregnancy was associated with maternal morbidity and preterm birth. American journal of obstetrics and gynecology. 2020;223(6):914.e1-.e15. Epub 2020/06/15.
[8] De Curtis M, Villani L, Polo A. Increase of stillbirth and decrease of late preterm infants during the COVID-19 pandemic lockdown. Archives of Disease in Childhood - Fetal and Neonatal Edition. 2021;106(4):456.
[9] Mor M, Kugler N, Jauniaux E, Betser M, Wiener Y, Cuckle H, et al. Impact of the COVID-19 Pandemic on Excess Perinatal Mortality and Morbidity in Israel. American journal of perinatology. 2021;38(4):398-403. Epub 2020/12/11.
[10] Khalil A, von Dadelszen P, Draycott T, Ugwumadu A, O’Brien P, Magee L. Change in the Incidence of Stillbirth and Preterm Delivery During the COVID-19 Pandemic. Jama. 2020;324(7):705-6.
[11] Meyer R, Bart Y, Tsur A, Yinon Y, Friedrich L, Maixner N, et al. A marked decrease in preterm deliveries during the coronavirus disease 2019 pandemic. American journal of obstetrics and gynecology. 2021;224(2):234-7. Epub 2020/10/15.
[12] Berghella V, Boelig R, Roman A, Burd J, Anderson K. Decreased incidence of preterm birth during coronavirus disease 2019 pandemic. American journal of obstetrics & gynecology MFM. 2020;2(4):100258-. Epub 2020/10/15.
[13] Caniglia EC, Magosi LE, Zash R, Diseko M, Mayondi G, Mabuta J, et al. Modest reduction in adverse birth outcomes following the COVID-19 lockdown. American journal of obstetrics and gynecology. 2021;224(6): 615.e1-.e12.
[14] Andrews MA, Areekal B, Rajesh KR, Krishnan J, Suryakala R, Krishnan B, et al. First confirmed case of COVID-19 infection in India: A case report. Indian J Med Res. 2020;151(5):490-2.
[15] Hindustan Times. India’s first coronavirus death is confirmed in Karnataka. 2020 March 12. In. Hindustan Times: India-News. Available at: https://www.hindustantimes.com/india-news/india-s-first-coronavirus-death-in-karnataka-confirmed/story-2ZJ6IuxJ38EiGndBq5pfHO.html. Accessed on 25 June 2021.
[16] Gettleman Jeffrey, Schultz Kai. Modi Orders 3-Week Total Lockdown for All 1.3 Billion Indians. 2020 March 24. In. The New York Times. Available at: https://www.nytimes.com/2020/03/24/world/asia/india-coronavirus lockdown.html. Accessed on 27 June 2021.
[17] Press Information Bureau, Government of India. PM calls for complete lockdown of entire nation for 21 days. 2020 March 24. Available at:https://pib.gov.in/PressReleseDetail.aspx?PRID=1608009. Accessed on 25 June 2021.
[18] Ministry of Home Affairs, Government of India. Guidelines on the measures to be taken by Ministries/ Departments of Government of India, State/Union Territory Governments and State/ Union Territory Authorities for containment of covid-19 Epidemic in the Country. 2020 March 24. Available at: https://www.mha.gov.in/sites/default/files/Guidelines.pdf. Accessed on 25 June 2021.
[19] Sharma N, Ghosh D. "Unlock1": Malls, Restaurants, Places of Worship to Reopen June 8. 2020 May 30. In. NDTV. Available at: https://www.ndtv.com/india-news/lockdown-extended-till-june- 30-malls-restaurants-can-reopen-from-june-8-except-in-containment-zones-2237910. Accessed on 25 June 2021.
[20] Deccan Herald. Covid-19 vaccination starts in India: 10 things to know. 2021 January 16. In. Deccan Herald. Available at: https://www.deccanherald.com/national/covid-19-vaccination-starts-in-india-10-things-to-know-939626.html. Accessed on 25 June 2021.
[21] Jamieson DJ, Honein MA, Rasmussen SA, Williams JL, Swerdlow DL, Biggerstaff MS, et al. H1N1 2009 influenza virus infection during pregnancy in the USA. Lancet (London, England). 2009;374(9688):451-8. Epub 2009/08/01.
[22] Donders F, Lonnée-Hoffmann R, Tsiakalos A, Mendling W, Martinez de Oliveira J, Judlin P, et al. ISIDOG Recommendations Concerning COVID-19 and Pregnancy. Diagnostics (Basel). 2020;10(4):243.
[23] Tang K, Gaoshan J, Ahonsi B, Ali M, Bonet M, Broutet N, et al. Sexual and reproductive health (SRH): a key issue in the emergency response to the coronavirus disease (COVID- 19) outbreak. Reproductive health. 2020;17(1):59. Epub 2020/04/25.
[24] Hedermann G, Hedley PL, Bækvad-Hansen M, Hjalgrim H, Rostgaard K, Poorisrisak P, et al. Danish premature birth rates during the COVID-19 lockdown. Arch Dis Child Fetal Neonatal Ed. 2021;106(1):93-5. Epub 2020/08/14.
[25] Philip RK, Purtill H, Reidy E, Daly M, Imcha M, McGrath D, et al. Unprecedented reduction in births of very low birthweight (VLBW) and extremely low birthweight (ELBW) infants during the COVID-19 lockdown in Ireland: a 'natural experiment' allowing analysis of data from the prior two decades. BMJ Glob Health. 2020;5(9).
[26] Zografaki I, Papamichail D, Panagiotopoulos T. Adverse effect of the financial crisis in Greece on perinatal factors. European journal of public health. 2018;28(6):1116-21. Epub 2018/05/23.
[27] Molina G, Weiser TG, Lipsitz SR, Esquivel MM, Uribe-Leitz T, Azad T, et al. Relationship Between Cesarean Delivery Rate and Maternal and Neonatal Mortality. Jama. 2015;314(21):2263-70. Epub 2015/12/02.
[28] International Institute for Population Sciences. National Family Health Survey (NFHS-4) 2015- 16: India Fact Sheet. [Internet]. Available at http://rchiips.org/nfhs/pdf/NFHS4/India.pdf. Accessed on 26 Jun 2021.
[29] Graham WJ, Afolabi B, Benova L, Campbell OMR, Filippi V, Nakimuli A, et al. Protecting hard-won gains for mothers and newborns in low-income and middle-income countries in the face of COVID-19: call for a service safety net. BMJ Glob Health. 2020;5(6):e002754.
[30] Bagchi S, Sabir H, Müller A, Reiter RJ. Effects of altered photoperiod due to COVID-19 lockdown on pregnant women and their fetuses. Chronobiology International. 2020;37(7):961-73.