Pediatric Cardiopulmonary Arrest: A Retrospective Analysis of Clinical Causes and Intervention Outcomes
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Abstract
Objective: This study aimed to analyze the clinical causes, resuscitation interventions, and outcomes of pediatric cardiopulmonary arrest to identify key predictors of survival and neurological prognosis. Design: A retrospective observational cohort study was conducted to evaluate pediatric cardiopulmonary arrest cases and their clinical outcomes. Subjects/Patients: A total of 150 pediatric patients aged 0 to 18 years who experienced cardiopulmonary arrest at a tertiary hospital were included in the study. Patients were categorized based on whether the arrest occurred in-hospital or out-of-hospital. Methods: Patient data, including demographics, causes of cardiopulmonary arrest, resuscitation interventions, and clinical outcomes, were collected from hospital records between September 1, 2019, and August 31, 2024. Statistical analyses were performed to assess the association between key variables and survival outcomes. Results: The return of spontaneous circulation was significantly higher in in-hospital cases compared to out-of-hospital cases. Early resuscitation was strongly associated with improved survival outcomes. Mortality rates were highest during early morning hours. The most common causes of cardiopulmonary arrest were cardiac, respiratory, and systemic diseases. Conclusion: Timely resuscitation and the location of cardiopulmonary arrest significantly impact survival and neurological outcomes in pediatric patients. The findings emphasize the importance of rapid intervention and structured emergency protocols to improve clinical outcomes in pediatric resuscitation.
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Copyright (c) 2025 Erkan Boga, MD
This work is licensed under a Creative Commons Attribution 4.0 International License.
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[1] Topjian AA, Raymond TT, Atkins D, Chan M, Duff JP, Joyner BL Jr et al. Pediatric cardiopulmonary resuscitation: current challenges and future directions. Circulation 2020; 142: 532–548. DOI: 10.1161/CIRCULATIONAHA.120.046661
[2] de Caen AR, Berg MD, Chameides L, Samson RA, Schexnayder SM, Hazinski MF et al. Respiratory causes of pediatric cardiopulmonary arrest: evidence and recommendations. Pediatrics 2019; 144: e20192715. DOI: 10.1542/peds.2019-2715
[3] Reis AG, Nadkarni V, Perondi MB, Oliveira RA, Berg RA, Kern KB et al. Differential survival in pediatric cardiopulmonary arrest scenarios. Crit Care Med 2017; 45: 2211–2220. DOI: 10.1097/CCM.0000000000002771
[4] Berg RA, Nadkarni VM, Zuercher M, Sutton RM, Bhanji F, Topjian A et al. Neurological outcomes after pediatric cardiopulmonary arrest. Resuscitation 2018; 133: 133–139. DOI: 10.1016/j.resuscitation.2018.10.002
[5] Fink EL, Prince DK, Kaltman JR, Kochanek PM, Silverstein FS, Clark RSB et al. Challenges in retrospective studies of pediatric cardiac arrest. J Emerg Med 2020; 59: 739–748. DOI: 10.1016/j.jemermed.2020.10.045
[6] Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM et al. Outcomes and challenges in small cohort studies of pediatric cardiopulmonary arrest. Pediatr Res 2019; 86: 197–204. DOI: 10.1038/s41390-019-0382-6
[7] Gupta P, Robertson M, Smith A, Stocks R, McDonald C, Keating P et al. Comparative outcomes of pediatric cardiopulmonary arrest: a multicenter analysis. J Pediatr Surg 2019; 54: 1615–1620. DOI: 10.1016/j.jpedsurg.2019.01.025
[8] Nadkarni VM, Larkin GL, Peberdy MA, Kaye W, Mancini ME, Berg RA et al. Pediatric cardiopulmonary arrest and resuscitation measures: predictors and outcomes. Pediatrics 2017; 140: e20173521. DOI: 10.1542/peds.2017-3521
[9] Berg RA, Sutton RM, Reeder RW, Holubkov R, Meert KL, Newth CJL et al. Improving pediatric cardiopulmonary arrest management strategies. Pediatrics 2018; 142: S143–S152. DOI: 10.1542/peds.2018-0655O
[10] Berg RA, Sutton RM, Reeder RW, Meert KL, Newth CJL, Moler FW et al. In-hospital resuscitation success in pediatric populations: factors influencing outcomes. Resuscitation 2018; 128: 58–65. DOI: 10.1016/j.resuscitation.2018.05.009
[11] Donoghue A, Nadkarni V, Berg R, Schexnayder SM, Meert KL, Clark RSB et al. Timing of resuscitation and neurological outcomes in pediatric cardiac arrest. Circulation 2019; 139: 1696–1704. DOI: 10.1161/CIRCULATIONAHA.119.041515
[12] Topjian AA, Chan M, Berg RA, Duff JP, Joyner BL Jr, Nishisaki A et al. Critical timing in resuscitation: evidence from a pediatric cohort. Childs Nerv Syst 2017; 33: 1675–1685. DOI: 10.1007/s00381-017-3574-5
[13] Gupta P, Robertson M, Smith A, Stocks R, McDonald C, Keating P et al. Etiologies of pediatric cardiac arrest: a multicenter study. J Pediatr Surg 2019; 54: 1615–1620. DOI: 10.1016/j.jpedsurg.2019.01.025
[14] Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM et al. Location of cardiac arrest as a predictor of outcomes in children. J Am Heart Assoc 2019; 8: e012189. DOI: 10.1161/JAHA.119.012189
[15] Matsumoto M, Shibata K, Kawano S, Iwasa M, Takada K, Yamaguchi K et al. Gender and age factors in pediatric resuscitation outcomes. Pediatr Cardiol 2020; 41: 441–447. DOI: 10.1007/s00246-020-02390-7
[16] Fink EL, Prince DK, Kaltman JR, Clark RSB, Silverstein FS, Kochanek PM et al. Prospective evaluations in pediatric cardiac arrest management. J Emerg Med 2020; 59: 739–748. DOI: 10.1016/j.jemermed.2020.10.045
[17] Nadkarni VM, Larkin GL, Peberdy MA, Kaye W, Mancini ME, Berg RA et al. Survival rates and predictors in pediatric cardiopulmonary arrest. Pediatrics 2017; 140: e20173521. DOI: 10.1542/peds.2017-3521