Role of Lab Parameters and Recurrence of Benign Paroxysmal Positional Vertigo (BPPV)
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Abstract
Background: The most prevalent peripheral vestibular condition, BPPV, is responsible for 17–42% of dizziness diagnoses in specialty clinics. It is defined as an abrupt, unusual feeling of motion and/or rotational vertigo that lasts less than a minute and is accompanied by the typical nystagmus. Numerous biochemical alterations in our bodies, such as a lack of vitamin D, can result in vestibular evoked myogenic potentials (VEMP) in the eyes and neck as well as dysfunction of the otolith organs. Methodology: A Longitudinal study was conducted in a tertiary care hospital in outpatient department of ENT. All the patients in the age group of 20 to 80 years with features of benign paroxysmal positional vertigo, involving posterior semi-circular canal, who attended the out-patient department were sample population. 70 participants were followed upto 6 months for recurrence of BPPV after manoeuvre and association with lab parameters were studied. Results: A total of 70 patients were considered for the study. Age group of participants ranged from 24-76 years with mean age of 53.1 ± 13.5 years. There was equal representation from both gender was observed. The mean TSH value among the study subjects were 4.6. The mean value of Hba1c among the patients who had recurrence of BPPV was 6.7, while the value among the study subjects were 6.2. Conclusion: there was an increased incidence of BPPV in subjects with serum vitamin D deficiency. Abnormal cholesterol and Blood sugar values did not show any association with recurrence of BPPV.
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Copyright (c) 2025 Dr. Malavika Raveendran, Dr. Amasa Viswanatha Reddy, Dr. M Sindhuja, Dr. Vidya K R

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[1] Kim JS, Zee DS. Clinical practice. Benign paroxysmal positional vertigo. N Engl J Med 2014; 370:1138-1147. https://doi.org/10.1056/NEJMcp1309481 10.1056/NEJMcp1309481
[2] Pérez P, Franco V, Cuesta P, et al. Recurrence of benign paroxysmal positional vertigo. Otol Neurotol 2012;33:437-443.https://doi.org/10.1097/MAO.0b013e3182487f78 10.1097/MAO.0b013e3182487f78
[3] Zucca G, Valli S, Valli P, et al. Why do benign paroxysmal positional vertigo episodes recover spontaneously? J Vestib Res 1998; 8:325-329.
[4] Brandt T, Huppert D, Hecht J, et al. Benign paroxysmal positioning vertigo: a long-term follow-up (6-17 years) of 125 patients. Acta Otolaryngol 2006; 126:160-163. https://doi.org/10.1080/00016480500280140 10.1080/00016480500280140
[5] Choi SJ, Lee JB, Lim HJ, et al. Clinical features of recurrent or persistent benign paroxysmal positional vertigo. Otolaryngol Head Neck Surg 2012; 147:919-924. https://doi.org/10.1177/0194599812454642. 10.1177/0194599812454642 Corrigendum. Otolaryngol Head Neck Surg 2013; 149:798. https://doi.org/10.1177/0194599813505840
[6] Dix MR, Hallpike CS. The Pathology, Symptomatology and Diagnosis of Certain Common Disorders of the Vestibular System. Proceedings of the Royal Society of Medicine. 1952;45(6):341-354.
[7] Manzari L. Enlarged vestibular aqueduct (EVA) related with recurrent benign paroxysmal positional vertigo (BPPV). Med Hypotheses 2008; 70:61-65. https://doi.org/10.1016/j.mehy.2007.04.032 10.1016/j.mehy.2007.04.032
[8] P M Picciotti, E De Corso et.al. Comorbidities and recurrence of benign paroxysmal positional vertigo: personal experience. DOI: 10.3109/14992027.2016.1143981
[9] Sreenivas V, Sima NH, Philip S. The Role of Comorbidities in Benign Paroxysmal Positional Vertigo. Ear Nose Throat J. 2021 Jun;100(5):NP225-NP230. doi: 10.1177/0145561319878546.
[10] Wada M, Naganuma H, Tokumasu K, Hashimoto S, Ito A, Okamoto M. Arteriosclerotic changes as background factors in patients with peripheral vestibular disorders. The International Tinnitus Journal,2008;14:131-4.