Clinical Profile, Biochemical Parameters, and Outcome of Acute Kidney Injury in Elderly Patients in a Tertiary Care Centre
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Abstract
Objective: To study the etiology, risk factors, clinical profile, complications, and outcomes of acute kidney injury (AKI) in elderly patients. Design: A prospective observational study. Subjects/Patients: Elderly patients (>60 years) admitted with AKI in medical wards and ICUs of a tertiary care hospital. Patients with chronic kidney disease were excluded. Methods: 101 patients with AKI (as per KDIGO criteria) were included. Data on demographics, clinical presentation, biochemical parameters, and outcomes were collected and analyzed using statistical tools. Patients were followed until discharge or death. Results: The mean age was 75.77±6.87 years, with a male-to-female ratio of 1.40:1. Hypertension (52.47%) and diabetes (51.49%) were common risk factors. Sepsis (29.70%) was the leading cause of AKI, followed by obstructive uropathy (21.78%). Pre-renal AKI was the most common type (45.54%). Mortality was 27.72%, with a higher risk in patients with multi-organ involvement, oliguria, hyperkalemia, and severe metabolic acidosis. Conclusion: AKI in the elderly is associated with significant morbidity and mortality, with sepsis being a major cause. Early recognition, prevention, and aggressive management of risk factors and infections are crucial to improving outcomes.
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Copyright (c) 2025 Girish Kolambe, Neelam Redkar, Smrati Bajpai, Pankaj Kharapkar, Ruqaiyah Vali, Raed A. Kalsekar, Alhad A. Mulkalwar, Kiran Kanhaiya Narang, Abhishek Saklecha
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