Abnormal Uterine Bleeding: Histopathological Patterns of Endometrium in Elderly Women
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Abstract
Objective: To evaluate endometrial histopathological patterns and observe their frequency in elderly women presenting with abnormal uterine bleeding. Design: Retrospective observational study. Subjects/Patients: 200 women aged over 40 years presenting with Abnormal Uterine Bleeding between 2017 and 2019. Methods: Endometrial samples from dilatation and curettage and hysterectomy specimens were fixed in 10% formalin, processed into paraffin blocks, stained with Haematoxylin and Eosin, and evaluated for histological patterns. Results: The maximum number of cases occurred in the fifth decade (57%). Menorrhagia was the most common clinical presentation (54%). Histopathologically, the proliferative pattern was the most frequent ovulatory finding (32.5%). Among anovulatory causes, simple endometrial hyperplasia without atypia was most common (27%). Endometrial carcinoma was identified in 1.5% of cases, primarily in the 61–65 age group. Conclusion: Histopathological evaluation of the endometrium is essential in perimenopausal and postmenopausal women with AUB to identify precise underlying causes and exclude malignancy.
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Copyright (c) 2026 Zalak Dholakiya, MD, Anamika Navadiya, MD, Md Hashmi Sabugar, MD
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