Complications and Comorbidities in Hospitalized Children with Severe Acute Malnutrition
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Abstract
Background: Severe Acute Malnutrition (SAM) remains a major cause of childhood morbidity and mortality in low- and middle-income countries, including India. Hospitalized children with SAM often present with multiple comorbidities and life-threatening complications, which significantly influence outcomes. Objectives: To evaluate the incidence, clinical profile, comorbidities, complications, and early outcomes among hospitalized children with Severe Acute Malnutrition. Methods: A hospital-based observational analytical study was conducted over one year at the Nutrition Rehabilitation Centre (NRC), Civil Hospital, Ahmedabad. Children aged 6–59 months fulfilling WHO criteria for SAM were enrolled. Sociodemographic details, feeding practices, anthropometry, clinical features, laboratory parameters, comorbidities, complications, duration of hospital stay, and outcomes were recorded and analyzed. Results: Out of 7,566 children screened, 211 (2.79%) were diagnosed with SAM. The majority were below two years of age (65%) and belonged to lower socioeconomic strata (55.92%). Inadequate exclusive breastfeeding was observed in 56.4% of children. Wasting and stunting were present in 70.14% and 49.28% respectively, with all children having MUAC <11.5 cm. Common comorbidities included nutritional anemia (73.93%), gastroenteritis (45.49%), pneumonia (29.85%), and septicemia (32.22%). Frequent complications were dehydration (48.34%), respiratory distress (39.81%), hypothermia (30.80%), and septic shock (18.95%). The mortality rate was 9.48%. Conclusion: Severe Acute Malnutrition continues to impose a substantial clinical burden among hospitalized children. Early identification, optimal feeding practices, timely management of infections, and comprehensive inpatient care are essential to reduce morbidity and mortality.
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Copyright (c) 2025 Dr. Dhara Gosai, Dr. Gargi H. Pathak, Dr. Achalkumar V. Raval

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[1] World Health Organization. Guideline: updates on the management of severe acute malnutrition in infants and children. Geneva: World Health Organization; 2013. Available from: https://www.who.int/publications/i/item/9789241506328
[2] Golden MH. The pathophysiology of severe malnutrition. In: Nestle Nutrition Workshop Series. 1997;37:1–21.
[3] Black RE, Victora CG, Walker SP, et al., Maternal and child undernutrition and overweight in low- and middle-income countries. Lancet. 2013;382:427-51.
[4] Manary MJ, Sandige HL. Management of acute moderate and severe childhood malnutrition. BMJ. 2008;337:a2180.
[5] Bhutta ZA, Ahmed T, Black RE, et al., What works? Interventions for maternal and child undernutrition and survival. Lancet. 2008; 371:417-40.
[6] International Institute for Population Sciences (IIPS) and ICF. National Family Health Survey (NFHS-5), India, 2019–21. Mumbai: IIPS; 2021.
[7] Singh MB, Fotedar R, Lakshminarayana J, Anand PK. Nutritional status of preschool children in desert areas of Rajasthan. Indian J Pediatr. 2006; 73:687-92.
[8] Pravati J, Patnaik L, Pati B. Clinical profile and incidence of severe acute malnutrition among hospitalized children in Eastern India. Int J Contemp Pediatr. 2016;3(2):476-80.
[9] Varsha G, Shashidhar HE, Rai BS. Prevalence and epidemiological correlates of severe acute malnutrition in hospitalized children. Indian J Child Health. 2017;4(1):44-8.
[10] Susheel KS, Radhakrishnan S, Dasappa L. Epidemiological and clinical profile of children with severe acute malnutrition admitted to a tertiary care hospital. Int J Med Sci Public Health. 2016;5(10):2125–9.
[11] Bhaskaran P, Jacob JJ, Varghese AM. Clinical presentation, anthropometry, and outcomes in children with severe acute malnutrition admitted to a tertiary care center. Indian Pediatr J. 2018;55(4):317-25.
[12] Chama GC, Rahman A, Suleman A. Socio-demographic determinants of severe acute malnutrition in under-five children attending an urban hospital. J Health Res. 2019;33(3):224-9.