Early Childbearing a Risk Factor for Gestational Hypertension in Rural Population in Chhattisgarh
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Abstract
Hypertension is the most common medical condition during pregnancy and is classified into four types: chronic hypertension, gestational hypertension, pre-eclampsia, and pre-eclampsia superimposed on chronic hypertension. Pre-eclampsia and gestational hypertension are major causes of maternal and perinatal morbidity and mortality.
Pre-eclampsia (PE) is a pregnancy-specific multisystem disorder, typically developing after 20 weeks of gestation. It is characterized by hypertension, proteinuria, and symptoms such as sudden weight gain. Although inadequate placentation begins early in pregnancy, clinical signs often appear later. If unmanaged, PE may progress to eclampsia, a severe complication involving seizures.
This 5-year retrospective study (2014–2018) assessed the prevalence of PE and eclampsia in rural Chhattisgarh. Among 991 pregnant women, 3.73% had pre-eclampsia and 4.33% had eclampsia. The highest prevalence occurred in women aged 19-23 years-72.9% for PE and 65.1% for eclampsia.
The high incidence in younger age groups is likely due to early marriage and childbearing, common in rural areas. Urbanization-related lifestyle changes may also contribute to the increasing risk of hypertensive disorders in pregnancy.
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Copyright (c) 2025 Kulshreshth Sinha, Dr Bharti Sahu, Sandeep Dasnam, Dr Varaprasad Kolla, Dr Andrea Kolla
This work is licensed under a Creative Commons Attribution 4.0 International License.
Creative Commons License All articles published in Annals of Medicine and Medical Sciences are licensed under a Creative Commons Attribution 4.0 International License.
Kulshreshth Sinha, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.
All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.
Dr Bharti Sahu, Seth Phoolchand Agrawal Smriti Mahavidhyalay, Raipur, Chhattisgarh, India.
Seth Phoolchand Agrawal Smriti Mahavidhyalay, Raipur, Chhattisgarh, India.
Sandeep Dasnam, Bank of America Merrill Lynch, USA.
Bank of America Merrill Lynch, USA.
Dr Varaprasad Kolla, Amity Univeristy, Raipur, Chhattisgarh, India.
Amity Univeristy, Raipur, Chhattisgarh, India.
Dr Andrea Kolla, Seth Phoolchand Agrawal Smriti Mahavidhyalay, Raipur, Chhattisgarh, India.
Seth Phoolchand Agrawal Smriti Mahavidhyalay, Raipur, Chhattisgarh, India.
[1] Liu, C., Cheng, P., Chang. S., Maternal Complications and Perinatal Outcomes associated with Gestational Hypertension and Severe Preeclampsia in Taiwanese Women. Journal Formes Medical Association 2008; 107(2):129-138.
[2] Duley L. The global impact of pre-eclampsia and eclampsia. Seminars in Perinatology, 2009 Jun;33 (3):130 –137.
[3] Steegers EA, von Dadelszen P, Duvekot JJ, Pijnenborg R. Pre-eclampsia. Lancet, 2010,21;376(9741):631–44. 3.
[4] Khan KS, Wojdyla D, Say L, Gülmezoglu AM, Van Look PF. WHO analysis of causes of maternal death: a systematic review. Lancet, 2006 Apr 1;367(9516):1066–1074.
[5] Chobanian AV, Barkris GL, Black HR, Cushman WC, Green LA, Izzo JL, Jr, et al. Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension. 2003;42:1206–52.
[6] Ananth CV, Keyes KM, Wapner RJ. Pre-eclampsia rates in the United States, 1980-2010: age-period-cohort analysis. BMJ 2013;347:f6564 doi: 10.1136/bmj.f6564.
[7] http://www.nhp.gov.in/disease/gynaecology -and obstetrics/preeclampsia
[8] Usha K, Sheriar NK. OBG in perspective, pregnancy induced hypertension. Orient longman Publications, Endocr Jr 2009; 56(8): 921-34
[9] Zibaeenazhad MJ, M Ghodsi, P Arab, Gholzom N. The prevalence of hypertensive disorders of pregnancy in Shiraz, Southern Iran. Iranian Cardiovascular Research Journal.2010;4:169-72.
[10] Liu, X., Ryan, Y., Liu,.Y., Zhang, W. Relationship between maternal age and hypertensive disorders in pregnancy Zhonghua YiXue Za Zhi. 2015 Jan 6;95(1):19-22.)
[11] Sheraz S, Shahzad S, Boota M. Eclampsia. Professional Medical Journal. 2006;13(1):27-31.
[12] ACOG Practice Bulletin No. 202: Gestational Hypertension and Preeclampsia. Obstet Gynecol 2019;133(1).
[13] Rather RH, Khan, SMS, Taing, S., Incidence of pregnancy-induced hypertension in block Hazratbal of district Srinagar, Jammu and Kashmir: ] a prospective longitudinal study, International Journal of Community Medicine and Public Health 2017 Jul;4(7):2333-2338
[14] Yucesoy G, Ozkan S, Bodur H, Tan T, Calıskan E, Vural B, et al Maternal and perinatal outcome in pregnancies complicated with hypertensive disorder of pregnancy: a seven year experience of a tertiary care center. Arch Gynecol Obstet 2005;273:43-9. [15834580]
[15] Pedersen, M., Halldorsson,TI., Olsen, SF., Hjortebjerg, D., Ketzel, M., Grandström, C., Raaschou-Nielsen, O., Sørensen, M., Impact of Road Traffic Pollution on Pre-eclampsia and Pregnancy-induced Hypertensive Disorders Epidemiology Vol 28, 201(100-106).
[16] Wu, M., Ries, J., Proietti, E., Vogt, D., Hahn, S., Hoesli, I. Development of Late-Onset Preeclampsia in Association with Road Densities as a Proxy for Traffic-Related Air Pollution. Fetal Diagn Ther 2016;39:21–27
[17] WHO. Make every mother and child count, in the world health report 2005. Geneva, Switzerland: World Health Organization; 2005.
[18] National Family Health Survey-4, 2015-2016
[19] Perez-Lopez FR, Chedraui P, Kravitz AS, Salazar-Pousada D, Hidalgo L. Present problems and controversies concerning pregnant adolescents. Open Access J Contracept. 2011;2:85–94.
[20] Salazar-Pousada D, Astudillo C, Gonzaga M, Hidalgo L, Perez-Lopez FR, Chedraui P. Intimate partner violence and psychoemotional disturbance among pregnant women admitted to hospital with prenatal complications. Int J Gynaecol Obstet. 2012;118(3):194–197.
[21] Traisrisilp K, Jaiprom J, Luewan S, Tongsong T. Pregnancy outcomes among mothers aged 15years or less. J Obstet Gynaecol Res. 2015; 41(11):1726–1731.
[22] Zárate A, Saucedo R, Valencia J, Manuel L, Hernández M. Early disturbed placental ischemia and hypoxia creates immune alteration and vascular disorder causing preeclampsia. Arch Med Res. 2014;45(7):519–524.
[23] Chang KJ, Seow KM, Chen Kuo-Hu. Preeclampsia: Recent Advances in Predicting, Preventing, and Managing the Maternal and Fetal Life-Threatening Condition. Int J Environ Res Public Health 2023 Feb 8;20(4):2994.
[24] Capdeville, G., Godinez-Medina, A., Copado-Mendoza, D.Y., Acevedo-Gallegos, S., Rodriguez-Bosch, M.R., Amaya-Guel, Y., Rodriguez-Sibaja, M.J. and Lumbreras-Marquez, M.I., Prediction of preeclampsia before 11th week of gestation: a secondary analysis of the ASPIRIN trial. AJOG Global Reports 2025, 5(3), p.100521.