Clinical Profile and Outcomes of COVID-19 in Elderly Patients of a Tertiary Care Centre
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Abstract
Objective: To assess the clinical profile, comorbidities, complications, and outcomes of elderly COVID-19 patients admitted to a tertiary care hospital in India. Design: Descriptive cross-sectional observational study. Subjects/Patients: 171 elderly patients (≥60 years) with RT-PCR-confirmed COVID-19. Methods: Patient records were reviewed for demographic details, symptoms, comorbidities, vitals, oxygen requirements, lab findings, complications, and outcomes. Statistical analysis included Chi-square and t-tests (p<0.05 considered significant). Results: Mean age was 71.01 ± 6.66 years; 49.7% were male. Common comorbidities included diabetes (45.6%) and hypertension (32.7%). Fever (79.5%) and cough (50.9%) were the most frequent symptoms. Hypoxia was present in 84.8%, and 25.1% required mechanical ventilation. Pneumonia (78.3%), ARDS (25.1%), and AKI (16.3%) were the main complications. Mortality was 25.1%, highest in those >80 years (58.8%). Hypertension, diabetes, ischemic heart disease, ≥3 comorbidities, and elevated WBC, CRP, LDH, IL-6, ferritin, and HbA1c were significantly associated with mortality. Conclusion: Elderly COVID-19 patients with comorbidities and elevated inflammatory or metabolic markers face a significantly higher risk of death. Early detection and aggressive management are essential to reduce mortality.
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Copyright (c) 2025 Neelam Redkar, Ganesh Karambelkar, Prakash Relwani, Suyash Vanarase, Saurabh Mandaknalli, Vineet Chandak, Alhad Mulkalwar
This work is licensed under a Creative Commons Attribution 4.0 International License.
Creative Commons License All articles published in Annals of Medicine and Medical Sciences are licensed under a Creative Commons Attribution 4.0 International License.
Neelam Redkar, Professor and Head, Department of Medicine, HBT Medical College & Dr RN Cooper Hospital, Mumbai, Maharashtra, India.
Professor and Head, Department of Medicine, HBT Medical College & Dr RN Cooper Hospital, Mumbai, Maharashtra, India.
Ganesh Karambelkar, Resident, Department of Nephrology, KEM Hospital, Pune, Maharashtra, India.
Resident, Department of Nephrology, KEM Hospital, Pune, Maharashtra, India.
Prakash Relwani, Associate Professor, Department of Medicine, HBT Medical College & Dr RN Cooper Hospital, Mumbai, Maharashtra, India.
Associate Professor, Department of Medicine, HBT Medical College & Dr RN Cooper Hospital, Mumbai, Maharashtra, India.
Suyash Vanarase, Resident, Department of Medicine, HBT Medical College & Dr RN Cooper Hospital, Mumbai, Maharashtra, India.
Resident, Department of Medicine, HBT Medical College & Dr RN Cooper Hospital, Mumbai, Maharashtra, India.
Saurabh Mandaknalli, Resident, Department of Medicine, HBT Medical College & Dr RN Cooper Hospital, Mumbai, Maharashtra, India.
Resident, Department of Medicine, HBT Medical College & Dr RN Cooper Hospital, Mumbai, Maharashtra, India.
Vineet Chandak, 4th Year MBBS Student, Seth G.S. Medical College and K.E.M Hospital, Mumbai, Maharashtra, India.
4th Year MBBS Student, Seth G.S. Medical College and K.E.M Hospital, Mumbai, Maharashtra, India.
Alhad Mulkalwar, Tutor, Department of Pharmacology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Dr. D.Y. Patil Vidyapeeth, (Deemed to be University), Pimpri, Pune, Maharashtra, India.
Tutor, Department of Pharmacology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Dr. D.Y. Patil Vidyapeeth, (Deemed to be University), Pimpri, Pune, Maharashtra, India.
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